SkinMedica Retinol Complex 0.5

Retinol Complex 0.5 is a retinol-based, night lotion formulated for retinol users which renews skin and diminishes the appearance of fine lines.


SkinMedica’s Age Defense Retinol Complex 0.5 enhances the skin’s texture to promote a brighter, more youthful complexion. Formulated for skin tolerant to retinol treatments, it stimulates collagen production and enhances faster cell renewal to minimize the appearance of fine lines and wrinkles. Algae extract ensures skin is soft, hydrated and protected against free-radical damage.


  1. Enhances skin tone, texture, and resiliency
  2. Diminishes appearance of fine lines and coarse wrinkles
  3. Appropriate for all skin types pre-conditioned by using Retinol Complex 0.25 or another retinoid product.


  • Retinol: smooths and refines skin’s texture and enhances radiance
  • PhytoShield™ Complex: an antioxidant complex, enhances skin texture and minimizes irritation

Weight 4.8 oz
Dimensions 2 × 2 × 6 in

How to Use

  • When to Apply 

    Apply In the evening after cleansing and toning and before applying your moisturizer. If a retinol product has never been used before, begin twice a week 2-3 days apart, gradually increasing frequency to every other night, and then advancing to each evening or as tolerated.

  • Where to Apply

    Apply to entire face. Avoid getting in eyes. If contact occurs, rinse eyes thoroughly with water.

    • Caution

      Do not use if you are pregnant, lactating or planning to become pregnant. Mild redness, peeling and irritation are expected when using this product. Use a daily sun protection with SPF 30 or higher and limit sun exposure while using this product and for a week following discontinuation.


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